COPD and Percussionaire treatment
Physiological response to intrapulmonary percussive ventilation in stable COPD patients.
Stefano Nava,1, Nicola Barbarito, Giancarlo Piaggi, Elisa De Mattia1, Serena Cirio Respiratory Medicine (2006) 100, 1526–1533
Objective: to assess the physiological response to IPV, on patients’ breathing pattern, inspiratory effort, lung mechanics and tolerance to ventilation.
Design: randomized trials using IPV through a face mask at different pressure/frequency combinations (1.2 bar/250 cycles/min; 1.8/250;1.2/350; 1.8/350)
Patients: Ten COPD patients.
Conclusions: -IPV was able to guarantee an adequate ventilation, while inducing a significant unloading of the diaphragm during the ‘‘low-frequency’’ trials. -Tolerance to ventilation and oxygen saturation were satisfactory and did not change during the different trials.
Intrapulmonary percussive ventilation in acute exacerbations of COPD patients with mild respiratory acidosis: a randomized controlled trial.
Frédéric Vargas, Hoang Nam Bui, Alexandre Boyer, Louis Rachid Salmi, Georges Gbikpi-Benissan, Hervé Guenard, Didier Gruson1 and Gilles Hilbert. Critical Care 2005,Vol 9 No 4
Design: randomized trial, standard treatment (control group) vs standard treatment plus IPV (IPV group)
Patients: Thirty-three patients with exacerbations of COPD.
Results: -Thirty minutes of IPV led to a significant decrease in respiratory rate, an increase in PaO2 and a decrease in PaCO2 (p < 0.05). -Exacerbation worsened in 6 out of 17 patients in the control group versus 0 out of 16 in the IPV group (p < 0.05). -The hospital stay was significantly shorter in the IPV group than in the control group (6.8 ± 1.0 vs. 7.9 ± 1.3 days, p < 0.05). |
